Mouse fever: symptoms and treatment

Infections carried by rodents can have very deplorable consequences for a person when they get into the body. One of these infections is murine fever, the symptoms of which appear in the initial stage in the form of an acute form of acute respiratory disease. Meanwhile, despite the direct relation to this category, the effects of infection are expressed not only in fever, as can be understood from the name, but also in kidney damage, general intoxication and thrombohemorrhagic syndrome. The danger of the disease lies in the fact that if you hit the kidneys with untimely started treatment, it can lead to a fatal outcome.

Virus Transmission

Vole mice, as well as Norwegian rats, act as carriers of the virus. In this case, the animals themselves do not get sick, but only suffer this virus. Isolation of it occurs through urine and feces of animals. Among the ways of infection are several of their types:

  • An airborne dust infection that inhales dust containing feces with a virus
  • Alimentary type of infection, in which food or water contaminated with secretions with a virus is used;
  • Contact type of infection, in which damaged skin contacts contaminated objects with a virus or directly with rodents infected with it.

There is no transfer of the virus from one person to another.

Mouse fever: symptoms, course of the disease

The duration of the incubation period can be on the order of 7-46 days, but the most frequent is the period of 21-25 days. The initial period, oligouric (characterized by hemorrhagic and renal manifestations), the period of polyuric and the period of convalescence are those actual periods of the course of the disease, which are characterized by murine fever. Symptoms of murine fever in children appear gradually, with their first manifestations can be seen only on the fifteenth, and even the twentieth day after the infection occurred. Among them are the following:

  1. Temperature rise up to 40 ° C;
  2. Muscle aches, joint pain
  3. Chills
  4. Nausea with alternating vomiting
  5. Migraines of a frequent occurrence type
  6. Visual impairment
  7. Severe haemorrhage of the gums, as well as bleeding from the nose

As for adults, murine fever has symptoms of a similar nature, the general appearance of which is as follows:

  • Temperature of about 40 ° C;
  • Severe headaches;
  • Increased sensitivity to light and pain in the eye area
  • Vagueness of surrounding objects, the feeling of having a «net» before your eyes
  • A rare pulse;
  • Lowering blood pressure;
  • Redness of the skin in the neck, face, eyes
  • Occurrence on 3-4 days of the disease of small spots of rash that focus in the area of ​​the sides of the trunk and underarms
  • Ocular hemorrhage;
  • Nasal bleeding;
  • Nausea and frequent vomiting.

Starting period . Its duration is 1-3 days, it is characterized by a fairly sharp start. Temperature, as we have already indicated, reaches about 40 ° C, often accompanied by chills. There is a headache strong enough in its manifestation, the patient’s condition is accompanied by dry mouth, general weakness. Inspection reveals the presence of signs of skin hyperemia (neck, face, upper thoracic parts), a conjunctiva appears, in some cases a hemorrhagic rash appears.

2-4 — 8-11 days of illness . As in the past period, the disease is characterized by fever, which lasts up to 4-7 days. A decrease in temperature does not lead to an improvement in the general state, moreover, it may even worsen. Typical manifestations for this period are pain in the lower back with varying degrees of severity. With the appearance of pain in the lumbar region, vomiting also occurs (6-8 or more times a day), while it is not associated with the use of drugs or food. There are also abdominal pains, often bloating. A characteristic manifestation of the disease is expressed in the defeat of the kidneys, which causes a puffy face, a positive symptom of Oligouria, the pasty of the eyelids.

9-13 days . The period is polyuric. Vomiting stops, abdominal and back pain gradually disappear, appetite and sleep come back to normal, the daily amount of urine released increases. Dry mouth and weakness persist, the recovery period is gradual, from 20-25 days.

Treatment of murine fever

Treatment of this disease occurs in the infectious ward at the hospital. For him, it is characteristic to appoint a bed rest for a period of 1-4 weeks. Appoint antipyretic, analgesic and antiviral drugs, as well as anti-inflammatory drugs. Additionally, infusion therapy is prescribed, if necessary, glucocorticoids and hemodialysis are used. The development of thrombohemorrhagic syndrome requires the use of anticoagulants. In addition, vitamins and the elimination of drugs that promote kidney damage are relevant.

To diagnose mouse fever, you should contact the infectious disease specialist, in addition, laboratory methods of testing (blood test, urine, PCR, coagulogram) may be assigned.